Checkpoint Inhibitors Side Effects

Fatigue weakness nausea confusion headache loss of appetite vision problems fever.

Checkpoint inhibitors side effects.

Other immune checkpoint inhibitors are under clinical evaluation. Since these drugs rev up your immune system they can cause a range of side effects including fatigue cough nausea loss of appetite rash and problems in your lungs kidneys intestines. Diarrhea pneumonitis inflammation in the lungs rashes and itchiness problems with some hormone levels kidney infections. Besides headache dizziness and apathy ataxia tremor paralysis myoclonus cognitive impairment speech disorders and even seizures may occur.

On average symptoms appear around nine weeks after starting treatment and may include. After about six months of therapy john tells you that over the past four weeks he has been experiencing increased fatigue weight gain insomnia and constipation. Paying careful attention to potential symptoms is therefore crucial. Occasional any grade toxicities in 5 20 of patients include fatigue headache arthralgia rash pruritus pneumonitis diarrhoea and or colitis hepatitis and endocrinopathies table 1.

Fatigue rash colitis infusion related reactions diarrhea asthenia arthralgias constipation decreased appetite cough dyspnea headache insomnia nausea pain including in the abdomen back and musculoskeletal system peripheral edema pneumonitis radiation pneumonitis pruritus pyrexia vomiting and weight loss. He says he figures these are just normal side effects of his medication. Checkpoint inhibitor associated neurological side effects are rare but potentially life threatening. Common side effects associated with currently approved checkpoint immunotherapies may include but are not limited to.

The most common side effects of checkpoint inhibitors are.